Article
Mechanisms underlying preferential assembly of heparan sulfate on glypican-1.
The Journal of biological chemistry - 9 Mar 2001
Chen R L, Lander A D
Abstract excerpt
Glypicans are major cell surface heparan sulfate proteoglycans, the structures of which are characterized by the presence of a cysteine-rich globular domain, a short glycosaminoglycan (GAG) attachment region, and a glycosylphosphatidylinositol membrane anchor. Despite strong evolutionary conservation of the globular domains of glypicans, no function has yet been attributed to them. By using a novel quantitative...
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