Article
Heparan sulfate proteoglycans.
Cold Spring Harbor perspectives in biology - 1 Jul 2011
Sarrazin Stephane, Lamanna William C, Esko Jeffrey D
Abstract excerpt
Heparan sulfate proteoglycans are found at the cell surface and in the extracellular matrix, where they interact with a plethora of ligands. Over the last decade, new insights have emerged regarding the mechanism and biological significance of these interactions. Here, we discuss changing views on the specificity of protein-heparan sulfate binding and the activity of HSPGs as receptors and coreceptors. Although...
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