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PAX Family, Master Regulator in Cancer

3 Jun 2025

Abstract excerpt

PAX genes, known as master regulators, encode paired box (PAX) proteins that govern key processes in organ development and are widely expressed in normal tissues. Notably, PAX proteins also play a pivotal role in both promoting and suppressing tumorigenesis. They influence essential cellular functions such as survival, proliferation, fate determination, differentiation, invasion, metastasis, and the formation of...

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PMID: 40506992
DOI: 10.3390/diagnostics15111420

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