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Article

PAX6, paired domain influences sequence recognition by the homeodomain.

The Journal of biological chemistry - 20 Dec 2002

Mishra Rajnikant, Gorlov Ivan P, Chao Lian Y, Singh Sanjaya, Saunders Grady F

Abstract excerpt

PAX6 functions as a transcription factor and has two DNA-binding domains, a paired domain (PD) and a homeodomain (HD), joined by a glycine-rich linker and followed by a proline-serine-threonine-rich (PST) transactivation region at the C terminus. The mechanism of PAX6 function is not clearly understood, and few target genes in vertebrates have been identified. In this report we described the functional analyses...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12388550
DOI: 10.1074/jbc.M206478200

Genes

PAX6

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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