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Article

Papillary urothelial hyperplasia is a clonal precursor to papillary transitional cell bladder cancer

1 Jan 2000

Abstract excerpt

Papilloma and papillary hyperplasia (PH) have been proposed to be the putative precursor lesions of papillary transitional-cell carcinoma of the urinary bladder. We examined 15 PH lesions and 4 papillomas for loss of heterozygosity (LOH) at 17 microsatellite markers on 9 chromosomal arms. Eight of 15 (53%) PHs were clonal, demonstrating LOH of at least 1 microsatellite marker. In contrast, none of the papillomas...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 11102896
DOI: 10.1002/1097-0215(20001120)89:6<514::aid-ijc8>3.0.co;2-h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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