Homozygous deletions of 9p21 in primary human bladder tumors detected by comparative multiplex polymerase chain reaction.

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Article

Homozygous deletions of 9p21 in primary human bladder tumors detected by comparative multiplex polymerase chain reaction.

Cancer research - 15 Mar 1994

Cairns P, Tokino K, Eby Y, Sidransky D

Abstract excerpt

Deletion mapping studies of primary bladder tumors have identified nonoverlapping areas of loss on each arm of chromosome 9, indicating that two distinct tumor suppressor loci are located on this chromosome. The deleted region on the p arm overlaps an area of 9p previously reported to be lost in...

Topics

Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 9
DNA
DNA, Neoplasm
Genes, Tumor Suppressor
Genetic Variation
Humans
Interferon-alpha
Neoplasm Staging
Polymerase Chain Reaction
Urinary Bladder Neoplasms

Source

Open in PubMed

Identifiers

PMID: 8137242

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8137242-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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