Article
Partial allelotype of carcinoma in situ of the human bladder.
Cancer research - 15 Nov 1995
Rosin M P, Cairns P, Epstein J I, Schoenberg M P, Sidransky D
Abstract excerpt
Carcinoma in situ (CIS) of the urinary bladder is an aggressive lesion that frequently progresses to an invasive tumor, yet the underlying molecular changes in this lesion are largely unknown. In this study, we microdissected 31 cases of CIS and examined them for loss of heterozygosity (LOH) on 13 chromosomal arms. Twenty-nine microsatellite markers were chosen for this analysis based on their location in regions...
Topics
- Alleles
- Carcinoma in Situ
- Chromosome Deletion
- Chromosomes, Human, Pair 9
- Humans
- Urinary Bladder Neoplasms
