Article
Evidence for alternative candidate genes near RB1 involved in clonal expansion of in situ urothelial neoplasia.
Laboratory investigation; a journal of technical methods and pathology - 1 Feb 2006
Kim Mi-Sook, Jeong Joon, Majewski Tadeusz, Kram Andrzej, Yoon Dong-Sup, Zhang Ruo-Dan, Li Jun-Zhi, Ptaszynski Konrad, Kuang Tang C, Zhou Jain-Hua, Sathyanarayana Ubaradka G, Tuziak Tomasz, Johnston Dennis A, Grossman Herbert B, Gazdar Adi F, Scherer Steven E, Benedict William F, Czerniak Bogdan
Abstract excerpt
In this paper, we present whole-organ histologic and genetic mapping studies using hypervariable DNA markers on chromosome 13 and then integrate the recombination- and single-nucleotide polymorphic sites (SNPs)-based deletion maps with the annotated genome sequence. Using bladders resected from patients with invasive urothelial carcinoma, we studied allelic patterns of 40 microsatellite markers mapping to all...
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