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Article

Production of macrophage-activated killer cells for targeting of glioblastoma cells with bispecific antibody to FcgammaRI and the epidermal growth factor receptor.

Cancer immunology, immunotherapy : CII - 1 Nov 2000

Wallace P K, Romet-Lemonne J L, Chokri M, Kasper L H, Fanger M W, Fadul C E

Abstract excerpt

OBJECTIVE: The aim was to determine the ability of macrophage-activated killer cells (MAK cells) obtained from peripheral blood of normal volunteers to kill glioblastoma multiforme (GBM) cell lines. Another goal was to investigate whether a bispecific antibody (bsAb) MDX-447, recognizing the high-affinity Fc receptor for IgG (FcgammaRI) and epidermal growth factor receptor (EGFR), would enhance MAK cell...

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Source

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Identifiers

PMID: 11092616
DOI: 10.1007/s002620000142
PMCID: PMC11037000

Genes

MAK
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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