Article
In Vitro Methods to Evaluate Macrophage Polarization and Function in Cancer.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2023
Ummarino Aldo, Anfray Clément, Maeda Akihiro, Andón Fernando Torres, Allavena Paola
Abstract excerpt
Tumor-associated macrophages (TAMs) play a key immunosuppressive role that limits the ability of the immune system to fight cancer and hinder the anti-tumoral efficacy of most treatments currently applied in the clinic. However, a key feature of macrophages is their phenotypical and functional plasticity, which called their attention as promising targets for therapeutic intervention based on their elimination or...
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