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Article

Analysis of hepatitis B virus genotypes and pre-core region variability during interferon treatment of HBe antigen negative chronic hepatitis B.

Journal of medical virology - 1 Jan 1996

Zhang X, Zoulim F, Habersetzer F, Xiong S, Trépo C

Abstract excerpt

The clinical importance of hepatitis B virus (HBV) genome variability has been reported recently. One example is the occurrence of hepatitis B virus pre-core mutants, which arise during spontaneous or interferon-induced seroconversion from HBeAg to anti-HBe and are thought to be selected by immune pressure. A survey of HBV pre-core mutants and viral genotypes in 35 HBeAg negative patients during interferon...

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Identifiers

PMID: 8825704
DOI: 10.1002/(SICI)1096-9071(199601)48:1<8::AID-JMV2>3.0.CO;2-E

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