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Article

Does APO epsilon4 correlate with MRI changes in Alzheimer's disease?

Journal of neurology, neurosurgery, and psychiatry - 1 Nov 2000

Doody R S, Azher S N, Haykal H A, Dunn J K, Liao T, Schneider L

Abstract excerpt

OBJECTIVE: To assess the relation between APO E genotype and MRI white matter changes in Alzheimer's disease. The APO epsilon4 allele is correlated with amyloid angiopathy and other neuropathologies in Alzheimer's disease and could be associated with white matter changes. If so, there should be a dose effect. METHODS: 104 patients with probable Alzheimer's disease (NINCDS-ADRDA criteria) in this Alzheimer's...

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Identifiers

PMID: 11032626
DOI: 10.1136/jnnp.69.5.668
PMCID: PMC1763391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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