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Article

Effect of the apolipoprotein E epsilon4 allele on white matter hyperintensities in dementia.

Stroke - 1 Jun 2000

Hirono N, Yasuda M, Tanimukai S, Kitagaki H, Mori E

Abstract excerpt

BACKGROUND AND PURPOSE: The clinical significance of the apoE epsilon4 allele in white matter changes in patients with dementia has been a subject of debate. We studied the association between the apoE epsilon4 allele and white matter hyperintensities (WMHs) before and after control for (1) potential vascular risk factors and (2) the presence of lacunar infarcts in patients with dementia. METHODS: The subjects...

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Source

Identifiers

PMID: 10835442
DOI: 10.1161/01.str.31.6.1263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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