Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cancer chemotherapy and somatic cell mutation.

Mutation research - 31 Oct 2000

Kubota M, Lin Y W, Hamahata K, Sawada M, Koishi S, Hirota H, Wakazono Y

Abstract excerpt

The occurrence of a second neoplasm is one of the major obstacles in cancer chemotherapy. The elucidation of the genotoxic effects induced by anti-cancer drugs is considered to be helpful in identifying the degree of cancer risk. Numerous investigations on cancer patients after chemotherapy have demonstrated: (i) an increase in the in vivo somatic cell mutant frequency (Mf) at three genetic loci, including...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Mutation
Share to Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Neoplasms, Second Primary

Source

Identifiers

PMID: 11027962
DOI: 10.1016/s1383-5742(00)00043-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cancer chemotherapy and somatic cell mutation.PMID 11027962Read ↗

Frequencies of HPRT mutants and micronuclei in lymphocytes of cancer patients under chemotherapy: a prospective study.Semantic proximity Read ↗

The human T-cell cloning assay: identifying genotypes susceptible to drug toxicity and somatic mutation.Semantic proximity Read ↗

What's new in cytostatic drug resistance and pathology.Semantic proximity Read ↗

Somatic-cell mutations as a possible predictor of cancer risk.Semantic proximity Read ↗

Flow cytometric measurements of somatic cell mutations in Thorotrast patients.Semantic proximity Read ↗

Prospective study of mutant frequencies at the hprt and T-cell receptor gene loci in pediatric cancer patients during chemotherapy.Semantic proximity Read ↗

A comparison of somatic mutational spectra in healthy study populations from Russia, Sweden and USA.Semantic proximity Read ↗

Somatic cell gene mutations in humans: biomarkers for genotoxicity.Semantic proximity Read ↗

[Results of and prospects for methods of determination of the frequency of mutant cells for glycophorin A and T-cell receptor loci to estimate long-term genotoxic effect of ionizing radiation].Semantic proximity Read ↗

Analysis of hprt gene mutation following anti-cancer treatment in pediatric patients with acute leukemia.Semantic proximity Read ↗

Spectrum of Pig-a mutations in T lymphocytes of rats treated with procarbazine.Semantic proximity Read ↗

Analysis of spontaneous, gamma ray- and ethylnitrosourea-induced hprt mutants in HL-60 cells with multiplex PCR.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.