Article
Somatic cell gene mutations in humans: biomarkers for genotoxicity.
Environmental health perspectives - 1 Oct 1993
Albertini R J, Nicklas J A, O'Neill J P
Abstract excerpt
Somatic cell gene mutations arising in vivo in humans provide biomarkers for genotoxicity. Four assays, each measuring changes in a different "recorder" gene, are available for detecting mutations of the hemoglobin (Hb) and glycophorin A (gpa) genes in red blood cells and the hypoxanthine-guanine...
Topics
- Erythrocytes
- Genetic Markers
- Genetic Variation
- Humans
- Mutation
- Phenotype
- T-Lymphocytes