Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

What's new in cytostatic drug resistance and pathology.

Pathology, research and practice - 1 Sept 1991

Dietel M

Abstract excerpt

A major problem in cytostatic treatment of malignant tumors is the development of chemoresistant cell clones. An increased understanding of chemoresistance related mechanisms, improved methods for the detection and localization of resistant cell populations including predictive conclusions on the effectiveness of cytostatic drugs would contribute to the advancement of anti-tumor strategies. This paper reviews...

Topics

Alkylating Agents
Antimetabolites
Antineoplastic Agents
Drug Resistance
Drug Screening Assays, Antitumor
Humans
Pathology
Phenotype
Platinum

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1754514
DOI: 10.1016/S0344-0338(11)80589-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1754514-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

What's new in cytostatic drug resistance and pathology.PMID 1754514Read ↗

Role of oncogenes in resistance and killing by cancer therapeutic agentsSemantic proximity Read ↗

Molecular aspects of cancer cell resistance to chemotherapy.Semantic proximity Read ↗

Overview of tumor cell chemoresistance mechanisms.Semantic proximity Read ↗

General Mechanisms of Resistance to Pharmacological Therapy Applied to Tumor CellsSemantic proximity Read ↗

Cisplatin and beyond: molecular mechanisms of action and drug resistance development in cancer chemotherapySemantic proximity Read ↗

Morphologic alterations in drug sensitive vs. drug resistant cells due to cytostatic application.Semantic proximity Read ↗

In vitro models to evaluate multidrug resistance in cancer cells: Biochemical and morphological techniques and pharmacological strategiesSemantic proximity Read ↗

Resistance to chemotherapy: new treatments and novel insights into an old problemSemantic proximity Read ↗

Proteins in cancer multidrug resistanceSemantic proximity Read ↗

Cisplatin Is a DNA-Damaging Antitumour Compound Triggering Multifactorial Biochemical Responses in Cancer Cells: Importance of Apoptotic PathwaysSemantic proximity Read ↗

Prediction of Broad Spectrum Resistance of Tumors towards Anticancer DrugsSemantic proximity Read ↗

Mechanisms of multidrug resistance in cancer treatment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.