Article
Somatic-cell mutations as a possible predictor of cancer risk.
Health physics - 1 May 1995
Akiyama M, Umeki S, Kusunoki Y, Kyoizumi S, Nakamura N, Mori T, Ishikawa Y, Yamakido M, Ohama K, Kodama T
Abstract excerpt
The somatic-mutation theory of carcinogenesis has received strong scientific support from results of recent studies on tumor-suppressor genes. We anticipated that people among the high risk for cancer group, either through exposure to various ionizing radiations or by virtue of unique genotypes, would also manifest increased frequencies of somatic mutation. This report presents the results of two somatic-mutation...
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