Article
Prospective study of mutant frequencies at the hprt and T-cell receptor gene loci in pediatric cancer patients during chemotherapy.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 1998
Sawada M, Kubota M, Lin Y W, Watanabe K, Koishi S, Usami I, Akiyama Y, Matsumura T, Furusho K
Abstract excerpt
Mutant frequencies (MFs) at the hypoxanthine phosphoribosyl transferase gene and the T-cell receptor (TCR) gene loci were evaluated in nine pediatric cancer patients before and during anticancer chemotherapy. The study population consisted of three patients with Hodgkin's disease, four patients w...
Topics
- Antineoplastic Combined Chemotherapy Protocols
- Child
- Child, Preschool
- Confidence Intervals
- Cyclophosphamide
- DNA Mutational Analysis
- Female
- Gene Frequency
- Hodgkin Disease
- Humans