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Article

The mismatch repair gene hMSH2 is mutated in the prostate cancer cell line LNCaP.

The Journal of urology - 1 Nov 2000

Leach F S, Velasco A, Hsieh J T, Sagalowsky A I, McConnell J D

Abstract excerpt

PURPOSE: Mismatch repair genes are responsible for the coordinated correction of misincorporated nucleotides formed during DNA replication. Inactivating and inherited mutations in the prototypic mismatch repair gene hMSH2 have been described in a cancer predisposition syndrome known as hereditary nonpolyposis colon cancer. Patients with hereditary nonpolyposis colon cancer are at increased risk for colon cancer...

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PMID: 11025778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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