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Article

The PON1 gene and detoxication.

Neurotoxicology - 1 Aug 2000

Furlong C E, Li W F, Brophy V H, Jarvik G P, Richter R J, Shih D M, Lusis A J, Costa L G

Abstract excerpt

It has been assumed since its discovery that serum paraoxonase (PON1) plays a major role in the detoxication of specific organophosphorus compounds. It was also assumed that individuals with low PON1 activity would be more susceptible to paraoxon/parathion poisoning than individuals with higher PON1 activity. Evidence supporting this hypothesis was provided by injection of rabbit PON1 into rodents. Injected PON1...

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Source

Identifiers

PMID: 11022865

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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