Article
Blood pressure QTL that differentiate Dahl salt-sensitive and spontaneously hypertensive rats.
Physiological genomics - 29 Jun 2000
Garrett M R, Saad Y, Dene H, Rapp J P
Abstract excerpt
Our purpose was to define quantitative trait loci (QTL) for blood pressure that differ between two widely used hypertensive rat strains, the Dahl salt-sensitive (S) rat and the spontaneously hypertensive rat (SHR). A genome scan was done on an F(2) (S x SHR) population fed 8% NaCl for 4 wk. Three blood pressure QTL were detected, one on each of rat chromosomes (chr) 3, 8, and 9. For the chr 3 QTL the SHR allele...
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