Article
Complete genome searches for quantitative trait loci controlling blood pressure and related traits in four segregating populations derived from Dahl hypertensive rats.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 1999
Kato N, Hyne G, Bihoreau M T, Gauguier D, Lathrop G M, Rapp J P
Abstract excerpt
The Dahl salt-sensitive rat is one of the principal animal models of hereditary hypertension. Genome-wide searches were undertaken to detect quantitative trait loci (QTLs) that influence blood pressure, cardiac mass, and body weight in four F2 populations derived from Dahl salt-sensitive rats and different inbred normotensive control strains of rat. We detected three QTLs associated with one or more of the...
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