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Article

Enhancement of hippocampal neurogenesis by lithium.

Journal of neurochemistry - 1 Oct 2000

Chen G, Rajkowska G, Du F, Seraji-Bozorgzad N, Manji H K

Abstract excerpt

Increasing evidence suggests that mood disorders are associated with a reduction in regional CNS volume and neuronal and glial cell atrophy or loss. Lithium, a mainstay in the treatment of mood disorders, has recently been demonstrated to robustly increase the levels of the cytoprotective B-cell lymphoma protein-2 (bcl-2) in areas of rodent brain and in cultured cells. In view of bcl-2's antiapoptotic and...

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Source

Identifiers

PMID: 10987856
DOI: 10.1046/j.1471-4159.2000.0751729.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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