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Article

Chronic Lithium Treatment Increases Telomere Length in Parietal Cortex and Hippocampus of Triple-Transgenic Alzheimer's Disease Mice.

Journal of Alzheimer's disease : JAD - 1 Jan 2018

Cardillo Giancarlo de Mattos, De-Paula Vanessa de Jesus Rodrigues, Ikenaga Eliza Hiromi, Costa Luciana Rodrigues, Catanozi Sergio, Schaeffer Evelin Lisete, Gattaz Wagner Farid, Kerr Daniel Shikanai, Forlenza Orestes Vicente

Abstract excerpt

Telomere length (TL) is a biomarker of cell aging, and its shortening has been linked to several age-related diseases. In Alzheimer's disease (AD), telomere shortening has been associated with neuroinflammation and oxidative stress. The majority of studies on TL in AD were based on leucocyte DNA, with little information about its status in the central nervous system. In addition to other neuroprotective effects,...

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Identifiers

PMID: 29614649
DOI: 10.3233/JAD-170838

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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