Article
Lithium enhanced cell proliferation and differentiation of mesenchymal stem cells to neural cells in rat spinal cord.
International journal of clinical and experimental pathology - 1 Jan 2015
Dong Bao-Tie, Tu Guan-Jun, Han Ya-Xin, Chen Yi
Abstract excerpt
Lithium has been shown to inhibit apoptosis of neural progenitor cells (NPCs) and promote differentiation of NPCs. However, there was rare data to discuss the effects of lithium on neural differentiation of mesenchymal stem cells (MSCs). Here, we investigated the potential promotion of lithium to MSC proliferation and neural differentiation in vitro and after transplanted into the ventral horn of rat spinal cord...
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