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Article

Effects of chronic haloperidol and clozapine treatment on neurogenesis in the adult rat hippocampus.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jun 2004

Halim Nader D, Weickert Cynthia Shannon, McClintock Benjamin W, Weinberger Daniel R, Lipska Barbara K

Abstract excerpt

It has been proposed that the therapeutic benefits of treatment with antidepressants and mood stabilizers may arise partially from their ability to stimulate neurogenesis. This study was designed to examine the effects of chronic antipsychotic treatment on cell proliferation and survival in the adult rat hippocampus. Haloperidol (0.05 and 2 mg/kg), clozapine (0.5 and 20 mg/kg), or vehicle were administered i.p....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15010699
DOI: 10.1038/sj.npp.1300422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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