Article
G-protein beta(3)-subunit C825T genotype and nephropathy in diabetes mellitus.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Sept 2000
Beige J, Ringel J, Distler A, Sharma A M
Abstract excerpt
BACKGROUND: Recent studies have identified a novel polymorphism (C825T) of the gene encoding the beta(3) subunit of heterotrimeric G proteins (G:beta(3)) which is associated with enhanced activation of G-proteins and appears to be more common in hypertensive patients and possibly contributes to decreased kidney allograft survival. METHODS: In the present study we examined the relationship between this genetic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
