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Article

The C825T polymorphism in the human G-protein beta3 subunit gene is not associated with diabetic nephropathy in Type I diabetes mellitus.

Diabetologia - 1 Nov 1998

Fogarty D G, Zychma M J, Scott L J, Warram J H, Krolewski A S

Abstract excerpt

In Type I (insulin-dependent) diabetes mellitus a genetic predisposition exists to nephropathy and is related to parental hypertension. Enhanced G-protein activation, a cellular phenotype observed in cultured cells from patients with essential hypertension, was recently documented in Type I diabetic subjects with nephropathy. This enhanced G-protein activation has been associated with a genetic variant in the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9833937
DOI: 10.1007/s001250051069

Genes

GNB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The C825T polymorphism in the human G-protein beta3 subunit gene is not associated with diabetic nephropathy in Type I diabetes mellitus.PMID 9833937Read ↗

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G-protein beta(3)-subunit C825T genotype and nephropathy in diabetes mellitus.Semantic proximity Read ↗

Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes.Semantic proximity Read ↗

G Protein β3 Subunit Variant and Essential Hypertension in JapaneseSemantic proximity Read ↗

G protein beta 3 subunit 825T allele, hypertension, obesity, and diabetic nephropathy.Semantic proximity Read ↗

G-protein beta3 subunit gene (GNB3) polymorphism 825C-->T in patients with hypertensive crisis.Semantic proximity Read ↗

The 825C/T polymorphism of the G-protein subunit beta3 does not influence blood pressure and renal function in kidney transplant recipients.Semantic proximity Read ↗

Transmission of G-protein beta3 subunit C825T alleles to offspring affected with end-stage renal disease.Semantic proximity Read ↗

G protein polymorphisms in hypertension, atherosclerosis, and diabetes.Semantic proximity Read ↗

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