Article
G-protein beta3 subunit gene C825T polymorphism is associated with arterial hypertension in Polish patients with type 2 diabetes mellitus.
Medical science monitor : international medical journal of experimental and clinical research - 1 Aug 2002
Dzida Grzegorz, Golon-Siekierska Patrycja, Puźniak Andrzej, Sobstyl Jacek, Biłan Andrzej, Mosiewicz Jerzy, Hanzlik Janusz
Abstract excerpt
BACKGROUND: Diabetes mellitus type 2 results from a complex of hereditary and environmental factors. Genes encoding elements of the G-protein system are candidate genes in hypertension and obesity. Since insulin uses G-sensitive mechanisms to enhance tissue glucose uptake and vasodilatation, the GNB3 gene may be a candidate gene in type 2 diabetes. The goal of our research was to determine if the C825T...
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