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Article

Association of insulin sensitivity and glucose tolerance with the c.825C>T variant of the G protein beta-3 subunit gene.

Journal of diabetes and its complications - 1 Jan 2000

Kopf Daniel, Cheng Li S-C, Blandau Petra, Hsueh Willa, Raffel Leslie J, Buchanan Thomas A, Xiang Anny H, Davis Richard C, Rotter Jerome I, Lehnert Hendrik

Abstract excerpt

UNLABELLED: The risk of macrovascular complications of diabetes mellitus is greatly enhanced by the presence of high blood pressure. In addition, hypertension and diabetes share insulin resistance as a common pathophysiological mechanism. Despite evidence for a common molecular genetic background of insulin resistance, glucose intolerance, and hypertension, few candidate genes have been shown to influence all of...

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Source

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Identifiers

PMID: 18413224
DOI: 10.1016/j.jdiacomp.2006.12.005
PMCID: PMC2695761

Genes

GNB3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of insulin sensitivity and glucose tolerance with the c.825C>T variant of the G protein beta-3 subunit gene.PMID 18413224Read ↗

G-protein beta3 subunit gene C825T polymorphism is associated with arterial hypertension in Polish patients with type 2 diabetes mellitus.Semantic proximity Read ↗

Interaction of the G protein beta 3 subunit T825 allele and the IRS-1 Arg972 variant in type 2 diabetes.Semantic proximity Read ↗

Association of the G protein beta3 subunit T allele with insulin resistance in essential hypertension.Semantic proximity Read ↗

The C825T polymorphism in the G-protein beta3 subunit gene and diabetic complications in IDDM patients.Semantic proximity Read ↗

Associations of a human G protein beta3 subunit dimorphism with insulin resistance and carotid atherosclerosis.Semantic proximity Read ↗

G-Protein beta(3) subunit C825T variant, nephropathy and hypertension in patients with type 2 (Non-insulin-dependent) diabetes mellitus.Semantic proximity Read ↗

An epidemiological study of blood pressure and metabolic phenotypes in relation to the Gbeta3 C825T polymorphism.Semantic proximity Read ↗

G-Protein β3-Subunit Gene C825T Polymorphism and Cardiovascular Risk: An Updated Review.Semantic proximity Read ↗

Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes.Semantic proximity Read ↗

G protein polymorphisms in hypertension, atherosclerosis, and diabetes.Semantic proximity Read ↗

G protein beta3 subunit 825T allele and its potential association with obesity in hypertensive individuals.Semantic proximity Read ↗

Association of the C825T polymorphism of the G-protein beta3 subunit gene with hypertension, obesity, hyperlipidemia, insulin resistance, diabetes, diabetic complications, and diabetic therapies among Japanese.Semantic proximity Read ↗

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