Article
The C825T polymorphism in the G-protein beta3 subunit gene and diabetic complications in IDDM patients.
Journal of human genetics - 1 Jan 2001
Shcherbak N S, Schwartz E I
Abstract excerpt
Complications of insulin-dependent diabetes mellitus (IDDM) are a major cause of morbidity and mortality; however, the mechanisms of their development are still to be elucidated. Genetic susceptibility contributes to the pathogenesis of nephropathy in IDDM. Enhanced G-protein activation, a cellul...
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