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Article

dackel acts in the ectoderm of the zebrafish pectoral fin bud to maintain AER signaling.

Development (Cambridge, England) - 1 Oct 2000

Grandel H, Draper B W, Schulte-Merker S

Abstract excerpt

Classical embryological studies have implied the existence of an apical ectodermal maintenance factor (AEMF) that sustains signaling from the apical ectodermal ridge (AER) during vertebrate limb development. Recent evidence suggests that AEMF activity is composed of different signals involving both a sonic hedgehog (Shh) signal and a fibroblast growth factor 10 (Fgf10) signal from the mesenchyme. In this study we...

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Source

Identifiers

PMID: 10976049
DOI: 10.1242/dev.127.19.4169

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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