Article
Interaction between Drosophila EGF receptor and vnd determines three dorsoventral domains of the neuroectoderm.
Development (Cambridge, England) - 1 Sept 1998
Yagi Y, Suzuki T, Hayashi S
Abstract excerpt
Neurogenesis in Drosophila melanogaster starts by an ordered appearance of neuroblasts arranged in three columns (medial, intermediate and lateral) in each side of the neuroectoderm. Here we show that, in the intermediate column, the receptor tyrosine kinase DER represses expression of proneural genes, achaete and scute, and is required for the formation of neuroblasts. Most of the early function of DER is likely...
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