Article
Fgf8 and Fgf3 are required for zebrafish ear placode induction, maintenance and inner ear patterning.
Mechanisms of development - 1 Nov 2002
Léger Sophie, Brand Michael
Abstract excerpt
The vertebrate inner ear develops from initially 'simple' ectodermal placode and vesicle stages into the complex three-dimensional structure which is necessary for the senses of hearing and equilibrium. Although the main morphological events in vertebrate inner ear development are known, the genetic mechanisms controlling them are scarcely understood. Previous studies have suggested that the otic placode is...
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