Article
The ectodysplasin pathway in feather tract development.
Development (Cambridge, England) - 1 Mar 2005
Houghton Leslie, Lindon Catherine, Morgan Bruce A
Abstract excerpt
The ectodysplasin pathway, comprising the ligand ectodysplasin, its receptor Edar and a dedicated death domain adaptor protein Edaradd, plays an important role in epidermal organ formation in mammals. Mutations in the genes encoding these proteins cause dysplasia or absence of teeth, sweat glands and hair follicles. However, the relative position of this pathway in the regulatory hierarchy directing follicle...
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