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Article

AP1 Transcription Factors in Epidermal Differentiation and Skin Cancer

1 Jan 2013

Abstract excerpt

AP1 (jun/fos) transcription factors (c-jun, junB, junD, c-fos, FosB, Fra-1, and Fra-2) are key regulators of epidermal keratinocyte survival and differentiation and important drivers of cancer development. Understanding the role of these factors in epidermis is complicated by the fact that each protein is expressed, at different levels, in multiple cells layers in differentiating epidermis, and because AP1...

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Identifiers

PMID: 23762562
DOI: 10.1155/2013/537028

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