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Article

A distal region of the human TGM1 promoter is required for expression in transgenic mice and cultured keratinocytes.

BMC dermatology - 5 Apr 2004

Phillips Marjorie A, Jessen Bart A, Lu Ying, Qin Qin, Stevens Mary E, Rice Robert H

Abstract excerpt

BACKGROUND: TGM1(transglutaminase 1) is an enzyme that crosslinks the cornified envelope of mature keratinocytes. Appropriate expression of the TGM1 gene is crucial for proper keratinocyte function as inactivating mutations lead to the debilitating skin disease, lamellar ichthyosis. TGM1 is also...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15061870
DOI: 10.1186/1471-5945-4-2
PMCID: PMC416661

Genes

TGM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15061870-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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