Article
Suppression of polydactyly of the Gli3 mutant (extra toes) by deltaEF1 homozygous mutation.
Development, growth & differentiation - 1 Aug 2000
Moribe H, Takagi T, Kondoh H, Higashi Y
Abstract excerpt
Digit patterning is established through multiple genetic interactions. Delta-crystallin enhancer/E2-box factor (deltaEF1) is a zinc finger and homeodomain containing repressor protein, and is expressed in the posterior half of the forelimb bud and in the entire hindlimb bud during the early stage of limb development. The 6EF1-deficient mutant mice display various skeletal abnormalities, among which inferior...
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