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Article

Long bone development requires a threshold of Hox function.

Developmental biology - 15 Aug 2014

González-Martín Ma Carmen, Mallo Moises, Ros Marian A

Abstract excerpt

The Hoxd(Del(11-13)) mutant is one of the animal models for human synpolydactyly, characterized by short and syndactylous digits. Here we have characterized in detail the cartilage and bone defects in these mutants. We report two distinct phenotypes: (i) a delay and change in pattern of chondrocyte maturation of metacarpals/metatarsals and (ii) formation of a poor and not centrally positioned primary ossification...

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Source

Identifiers

PMID: 24930703
DOI: 10.1016/j.ydbio.2014.06.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Long bone development requires a threshold of Hox function.PMID 24930703Read ↗

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