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Article

Five exon 1 variants of mu opioid receptor and vulnerability to alcohol dependence.

Polish journal of pharmacology - 1 Jan 2000

Gscheidel N, Sander T, Wendel B, Heere P, Schmidt L G, Rommelspacher H, Hoehe M R, Samochowiec J

Abstract excerpt

The human mu opioid receptor (hMOR) gene is a prime candidate gene responsible for addictive disorders. The present association study tested the hypothesis that hMOR exon 1 variants elicit susceptibility to alcohol dependence. We have analyzed five nucleotide changes in exon 1 of the hMOR gene. Three of them are in the 5'untranslated region of exon 1 at positions -172G/T,-111C/T and -3 8C/A, the remaining two...

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PMID: 10949117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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