Human mu-opioid receptor variation and alcohol dependence.

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Article

Human mu-opioid receptor variation and alcohol dependence.

Alcoholism, clinical and experimental research - 1 Dec 1998

Sander T, Gscheidel N, Wendel B, Samochowiec J, Smolka M, Rommelspacher H, Schmidt L G, Hoehe M R

Abstract excerpt

Mu-Opioid receptor-mediated neurotransmission is involved in the reward, tolerance, and withdrawal effects of alcohol. The present association study tested the hypothesis that the common Asn40Asp substitution polymorphism in the N-terminal domain of the human mu-opioid receptor (OPRM) confers vul...

Topics

Adult
Alcohol Withdrawal Delirium
Alcoholism
Alleles
Female
Gene Frequency
Genetics, Population
Genotype
Germany
Humans
Male
Middle Aged
Polymorphism, Genetic
Receptors, Opioid, mu
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 9884158

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9884158-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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