Article
Evidence for modulation of genes involved in vascular adaptation by prolonged exposure of endothelial cells to shear stress
1 Aug 2000
Abstract excerpt
OBJECTIVE: Shear stress is known to modulate gene expression. However, the molecular link between blood flow and long-time vessel adaptation is still unclear. In this study, the variations of gene expression by prolonged shear stress exposure was investigated in order to identify genes possibly involved in flow dependent vascular adaptation. METHODS: Human umbilical vein endothelial cells (HUVECs) were exposed to...
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