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Article

Adaptation of the endothelium to fluid flow: in vitro analyses of gene expression and in vivo implications.

Vascular medicine (London, England) - 1 Feb 2004

Wasserman Scott M, Topper James N

Abstract excerpt

Biomechanical forces generated by blood flow play an important role in the pathogenesis of vascular disease. For example, regions exposed to non-uniform shear stresses develop early atherosclerotic lesions while areas exposed to uniform shear stresses are protected. A variety of in vitro flow app...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15230487
DOI: 10.1191/1358863x04vm521ra

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15230487-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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