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Global Analysis of Shear Stress-Responsive Genes in Vascular Endothelial Cells

1 Jan 2003

Abstract excerpt

DNA microarray gene expression analysis was conducted in human umbilical vein endothelial cells (HUVECs) and coronary artery endothelial cells (HCAECs) exposed to laminar or turbulent shear stress. Approximately 3% of the total 5600 gene in HUVECs and HCAECs increased their expression more than two-fold or decreased it to less than half the static control in response to an arterial level of laminar shear stress...

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PMID: 14718748
DOI: 10.5551/jat.10.304

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