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Article

Mapping and determination of the cDNA sequence of the Erc gene preferentially expressed in renal cell carcinoma in the Tsc2 gene mutant (Eker) rat model.

Biochemical and biophysical research communications - 18 Aug 2000

Yamashita Y, Yokoyama M, Kobayashi E, Takai S, Hino O

Abstract excerpt

The Eker rat develops hereditary renal carcinomas (RCs) due to two hit mutations of the tumor suppressor gene, Tsc2. We previously identified using representational difference analysis (RDA), four genes that were expressed more abundantly in an Eker rat RC cell line than in normal kidney tissue. One gene, Erc (expressed in renal carcinoma) showed sequence homology to the mouse and human megakaryocyte potentiating...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 10944454
DOI: 10.1006/bbrc.2000.3280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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