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Article

Renal carcinogenesis: genotype, phenotype and dramatype.

Cancer science - 1 Feb 2003

Hino Okio, Kobayashi Toshiyuki, Momose Shuji, Kikuchi Yasushi, Adachi Hiroyuki, Okimoto Kazuo

Abstract excerpt

Cancer is a heritable disorder of somatic cells. Environment and heredity are both important in the carcinogenic process. The Eker rat model of hereditary renal carcinoma (RC) is an example of a Mendelian dominantly inherited predisposition to a specific cancer in an experimental animal. Forty years after the discovery of the Eker rat in Oslo, we and Knudson's group independently identified a germline...

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Source

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Identifiers

PMID: 12708488
DOI: 10.1111/j.1349-7006.2003.tb01410.x
PMCID: PMC11160249

Genes

TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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