Article
Identification of tuberous sclerosis 2 messenger RNA splice variants that are conserved and differentially expressed in rat and human tissues.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Sept 1995
Xiao G H, Jin F, Yeung R S
Abstract excerpt
Tuberous sclerosis 2 (Tsc2) gene is the target of a germline insertion in the Eker rat model of inherited cancer susceptibility. This tumor suppressor gene, when mutated, gives rise to a spectrum of epithelial and nonepithelial neoplasms in the rat, as well as multisystem involvement of hamartoma...
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