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Article

p12(DOC-1) is a novel cyclin-dependent kinase 2-associated protein.

Molecular and cellular biology - 1 Sept 2000

Shintani S, Ohyama H, Zhang X, McBride J, Matsuo K, Tsuji T, Hu M G, Hu G, Kohno Y, Lerman M, Todd R, Wong D T

Abstract excerpt

Regulated cyclin-dependent kinase (CDK) levels and activities are critical for the proper progression of the cell division cycle. p12(DOC-1) is a growth suppressor isolated from normal keratinocytes. We report that p12(DOC-1) associates with CDK2. More specifically, p12(DOC-1) associates with the monomeric nonphosphorylated form of CDK2 (p33CDK2). Ectopic expression of p12(DOC-1) resulted in decreased cellular...

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Identifiers

PMID: 10938106
DOI: 10.1128/MCB.20.17.6300-6307.2000
PMCID: PMC86104

Genes

CDK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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