Article
A novel yeast screen for mitotic arrest mutants identifies DOC1, a new gene involved in cyclin proteolysis.
Molecular biology of the cell - 1 Oct 1997
Hwang L H, Murray A W
Abstract excerpt
B-type cyclins are rapidly degraded at the transition between metaphase and anaphase and their ubiquitin-mediated proteolysis is required for cells to exit mitosis. We used a novel enrichment to isolate new budding mutants that arrest the cell cycle in mitosis. Most of these mutants lie in the CD...
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