Article
Widespread susceptibility among inbred mouse strains to the induction of lupus autoantibodies by pristane.
Clinical and experimental immunology - 1 Aug 2000
Satoh M, Richards H B, Shaheen V M, Yoshida H, Shaw M, Naim J O, Wooley P H, Reeves W H
Abstract excerpt
Unlike other agents associated with drug-induced lupus, the isoprenoid alkane pristane induces autoantibodies pathognomonic of lupus, including anti-Sm, anti-dsDNA, and anti-ribosomal P in BALB/c and SJL/J mice. The susceptibility of other strains of mice to pristane-induced lupus is unknown and is the focus of the present study. Anti-nRNP/Sm, anti-Su, and anti-ribosomal P autoantibodies were produced by most...
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